Protection of kidney

Chronic renal insufficiency (CRI) is one of the most common causes of death in dogs and cats. Approximately 40% of cats over 15 years and about 20% of old dogs suffering from chronic renal insufficiency.

This manifestuje progressive loss of functional renal parenchyma, which may be offset by short-term compensatory mechanisms. Long-term compensatory mechanisms are harmful and lead to further significant loss of kidney function.

Initial stage

Initial lesions are the cause of functional nephron damage. In young animals the majority of lesions vrozeneho origin in older animals to obtain, which may be either toxic or infectious origin.

Clinical symptoms

CRI clinically detectable symptoms appear until the final stage of the disease, ie. when at least 70% nephron is poskozeno.Toto stage is known as uremicky syndrome. Its symptoms are due to retention uremickych toxins,which largely arise catabolism of proteins and amino acids.

Symptoms are patognomicke for CRI and varies with the dog and cat food. To determine the exact diagnosis is necessary to further investigations.

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