Nadledvinky

In our nine-year-old girls found a poodle crosses veterinarian disorder adrenal glands. They said the drugs, which destroys part of adrenal glands, but are quite expensive. Not even any other option of treatment?

Failure of adrenal gland, which you mention is probably the hyperadrenokorticismus, or Cushing's syndrome. It is a disease in which the body produces excess steroid hormones especially cortisol.

This disease is mainly a matter of older dogs. Among the breeds with a higher incidence of this disorder include the poodle, and dachshunds. Cortisol in the adrenal gland is composed of an instruction from the brain area called the pituitary. Pituitary sends a signal to adrenal hormone cortisol begin to form. When is it enough, the body sends another signal back to the pituitary, the so-called feedback, and it stops transmitting signals necessary for the production of cortisol in the adrenal gland. So it works in healthy individuals. When the disease hyperadrenokorticismem two situations may arise.Hypophysis not sent any signals yet, and adrenal gland cortisol. It is therefore a disorder of adrenal itself, in which case we speak of primary, peripheral hyperadrenokorticismu. In the second case does not work feedback and pituitary still sends a signal for the production of cortisol and adrenal fulfill this order and are healthy. In the pituitary failure is a secondary, or if central hyperadrenokorticismus. In both cases, there is a significant overproduction of cortisol. Special group are patients who are steroid hormones administered for therapeutic purposes, eg allergies. In these animals the pituitary adrenal function and hormone levels artificially increased use one tablet. This condition is called iatrogenic hyperadrenokorticismus.

In dogs,affected Cushingovym syndrome is most striking their poor sparse hair. Lysiny appear symmetrically on the sides, shoulders, abdomen and scum and weaknesses in contrast to normal osrstenymi limbs and head. On the bare sites in the body increases production of skin and form the black dots, called komedony. The skin is significantly weakened, losing its elasticity and the dry surface. Often likened to the parchment. On neosrstenych places is more skin irritation and may darken. Sometimes there to focal calcification. Another very common symptom is centripetal obesity. These dogs have a thin nozkach soudeckovite chubby body and the head is again unchanged. The owner often comes with a dog, which starts at home pomocovat.Increased levels of steroid hormones prevents water retention in the body and the animal produces more urine, which requires more frequent venceni. Excessive water loss supplements drink. Increased appetite is to feed intake. Most animals hyperadrenokorticismem has decreased libido sexualis, which is reflected mainly prolongation of intervals between haranim to complete interruption during the sexual cycle. For longer lasting disease are muscle weakness and progressive loss of muscle mass. Cortisol has an impact on raising blood sugar level. Therefore, many patients with Cushingovym syndrome also suffer from diabetes.

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